Engineering cellular metabolism for regenerative medicine: The role of bioenergetic materials

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Published: 2025-12-30
DOI: https://doi.org/10.61882/ijbwr.1.4.49
Keywords:
Bioenergetic materials, Mitochondrial function, Redox balance, Regenerative medicine

Main Article Content

Seyed Ali Hosseini
Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran
https://orcid.org/0009-0008-6144-0073
Sina Salem Ahim
School of Medicine, Fasa University of Medical Sciences, Fasa, Iran
https://orcid.org/0009-0008-2452-434X
Ali Aghajan
Department of Physics, University of Hamburg, D-20355, Hamburg, Germany
https://orcid.org/0009-0004-5148-6351

Abstract

No abstract.

Article Details

Issue

VOL 1, NO 4 (2025). Oct-Dec

Section

Letter
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

Hosseini, S. A., Salem Ahim, S., & Aghajan, A. . (2025). Engineering cellular metabolism for regenerative medicine: The role of bioenergetic materials. Iranian Journal of Burns and Wound Research, 1(4), 156-157. https://doi.org/10.61882/ijbwr.1.4.49
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References

[1] Liu H, Du Y, St-Pierre JP, Bergholt MS, Autefage H, Wang J, et al. Bioenergetic-active materials enhance tissue regeneration by modulating cellular metabolic state. Sci Adv. 2020;6(13):eaay7608.

DOI: 10.1126/sciadv.aay7608 PMID: 32232154

[2] Liu H, Wei J, Xiao S, Jin S, Yuan L, Wen J, et al. Regulation Energy Metabolism of Fiber Scaffolds Orchestrates Osteoimmunomodulation and Angio/Osteogenesis. Small. 2025;21(18):e2409747.

DOI: 10.1002/smll.202409747 PMID: 40135330

[3] Chakrabarty RP, Chandel NS. Mitochondria as Signaling Organelles Control Mammalian Stem Cell Fate. Cell Stem Cell. 2021;28(3):394-408.

DOI: 10.1016/j.stem.2021.02.011 PMID: 33667360

[4] Li X, Jiang O, Chen M, Wang S. Mitochondrial homeostasis: shaping health and disease. Current Medicine. 2024;3(1):5.

DOI: 10.1007/s44194-024-00032-x

[5] Pezzini I, Marino A, Del Turco S, Nesti C, Doccini S, Cappello V, et al. Cerium oxide nanoparticles: the regenerative redox machine in bioenergetic imbalance. Nanomedicine (Lond). 2017;12(4):403-416.

DOI: 10.2217/nnm-2016-0342 PMID: 28000542

[6] Liu J, Zhou Z, Hou M, Xia X, Liu Y, Zhao Z, et al. Capturing cerium ions via hydrogel microspheres promotes vascularization for bone regeneration. Mater Today Bio. 2024;25:100956.

DOI: 10.1016/j.mtbio.2024.100956 PMID: 38322657

[7] Jiang X, Wang W, Tang J, Han M, Xu Y, Zhang L, et al. Ligand-Screened Cerium-Based MOF Microcapsules Promote Nerve Regeneration via Mitochondrial Energy Supply. Adv Sci (Weinh). 2024;11(6):e2306780. DOI: 10.1002/advs.202306780 PMID: 38037294

[8] Liu Z, Li Y, Li C, Yu L, Chang Y, Qu M. Delivery of coenzyme Q10 with mitochondria-targeted nanocarrier attenuates renal ischemia-reperfusion injury in mice. Mater Sci Eng C Mater Biol Appl. 2021;131:112536.

DOI: 10.1016/j.msec.2021.112536 PMID: 34857313

[9] Xu X, Pang Y, Fan X. Mitochondria in oxidative stress, inflammation and aging: from mechanisms to therapeutic advances. Signal Transduct Target Ther. 2025;10(1):190.

DOI: 10.1038/s41392-025-02253-4 PMID: 40500258

[10] Zhang H, Ryu D, Wu Y, Gariani K, Wang X, Luan P, et al. NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science. 2016;352(6292):1436-43. DOI: 10.1126/science.aaf2693 PMID: 27127236